Immune System Modelling and Simulation Book PDF, ePub eBook

Join our eBook service for unlimited books & audiobooks. Get a free 7 day subscription! ↓↓↓↓↓


Book Descriptions:

The book describes a computational model of the immune system reaction, C-ImmSim, built along the lines of the computer model known as the Celada-Seiden model (CS-model). The computational counterpart of the CS-model is called IMMSIM which stands for IMMune system SIMulator. IMMSIM was written in 1992 by the physicist Phil E. Seiden and the immunologist Franco Celada. This model was built around the idea of developing a computerized system to perform experiments similar in vivo experiments; a tool developed to help biologists testing theories and hypothesis about how the immune system works.

C-ImmSim is best viewed as a collection of models in a single program. It incorporates the principal core facts of today’s immunological knowledge, such as the diversity of specific elements, MHC restriction, clonal selection, thymic education of T cells, antigen processing and presentation (both the cytosolic and endocytic pathways are implemented), cell-cell cooperation, homeostasis of cells created by the bone marrow, hyper mutation of antibodies, maturation of the cellular and humoral response, and memory. Besides, an antigen can represent a bacterium, a virus, or an allergen or a tumor cell. C-ImmSim has been recently customized to simulate the HIV-1 infection. Moreover,　it can simulate the immunotherapy for cancer. These features are all present in the code and people can choose to turn them on and off at compiling time.

The book presents the basic model as well as the various customizations to implement the description of different diseases and the way they have been used in practice to produce new knowledge either from hypothesis or from lab-experiment data. In this respect, the book can be used as a practical guide to implement a computational model with which to study a specific disease and to try to address realistic clinical questions.

Immune System Modelling and Simulation by Filippo Castiglione, Franco Celada

From reader reviews:

Floyd Wyatt:

A lot of people always spent their very own free time to vacation or go to the outside with them friends and family or their friend. Are you aware? Many a lot of people spent they free time just watching TV, or maybe playing video games all day long. In order to try to find a new activity this is look different you can read a new book. It is really fun for yourself. If you enjoy the book that you simply read you can spent all day every day to reading a guide. The book Immune System Modelling and Simulation it is extremely good to read. There are a lot of people who recommended this book. These were enjoying reading this book. Should you did not have enough space to deliver this book you can buy typically the e-book. You can m0ore quickly to read this book from a smart phone. The price is not to fund but this book features high quality.

Sandra Leggett:

In this time globalization it is important to someone to receive information. The information will make anyone to understand the condition of the world. The fitness of the world makes the information quicker to share. You can find a lot of references to get information example: internet, newspapers, book, and soon. You can view that now, a lot of publisher that print many kinds of book. The particular book that recommended to you is Immune System Modelling and Simulation this reserve consist a lot of the information on the condition of this world now. This particular book was represented so why is the world has grown up. The terminology styles that writer use for explain it is easy to understand. Typically the writer made some exploration when he makes this book. Here is why this book acceptable all of you.

April Hanson:

Many people spending their moment by playing outside using friends, fun activity along with family or just watching TV the whole day. You can have new activity to spend your whole day by reading a book. Ugh, do you consider reading a book really can hard because you have to bring the book everywhere? It all right you can have the e-book, delivering everywhere you want in your Mobile phone. Like Immune System Modelling and Simulation which is getting the e-book version. So , try out this book? Let's notice.

Annie Fowler:

You can get this Immune System Modelling and Simulation by look at the bookstore or Mall. Simply viewing or reviewing it could possibly to be your solve trouble if you get difficulties for your knowledge. Kinds of this e-book are various. Not only simply by written or printed but in addition can you enjoy this book through e-book. In the modern era just like now, you just looking of your mobile phone and searching what their problem. Right now, choose your personal ways to get more information about your e-book. It is most important to arrange you to ultimately make your knowledge are still update. Let's try to choose right ways for you.